Fig. 1

Effects of functional SNPs and CAAA haplotype in AGXT2 on ADMA concentrations. Average ADMA concentrations were tested by one-way ANOVA or the Kruskal–Wallis test among the a rs37370 (p = 0.222), b rs37369 (p = 0.238), c rs16899974 (p = 0.986), d rs180749 (p = 0.001), and e CAAA haplotypes (p = 0.083). The horizontal bar represents the mean ± standard error. Statistical significance based on a post hoc test among the two groups is indicated by an asterisk (*). CAAA was predicted by each allele of the four SNPs as follows: rs37370 (c), rs37369 (a), rs180749 (a), and rs16899974 (a). SNP, single nucleotide polymorphism