Volume 15 Supplement 2

Abstracts from the 2nd International Genomic Medicine Conference (IGMC 2013)

Meeting abstracts

Edited by Stephen Scherer, Muhammad Abu-Elmagd, Ashraf Dallol, Jerry Shay, Mohammed Al-Qahtani, Abdelbaset Bauhmedia, Hans-Juergen Schulten, Farid Ahmed and Mourad Assidi

Publication of this supplement has been funded by Centre of Excellenece in Genomic Medicine Research (CEGMR), King Abdulaziz University (KAU). The Supplement Editors declare that they have no competing interests.

2nd International Genomic Medicine Conference (IGMC 2013). Go to conference site.

Jeddah, Kingdom of Saudi Arabia24-27 November 2013

Concatenated PDF 15S2

Page 1 of 2

Ion channels: their discovery, their function, and their role in disease

Authors: Erwin Neher

Citation: BMC Genomics 2014 15(Suppl 2):O1

Content type: Oral presentation

Published on: 2 April 2014
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Saudi national science, technology and innovation plan towards knowledge based economy

Authors: Abdulaziz M. Al-Swailem

Citation: BMC Genomics 2014 15(Suppl 2):O2

Content type: Oral presentation

Published on: 2 April 2014
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Therapeutic targeting truncated adenomatous polyposis coli (APC) proteins for the selective killing of colorectal cancer cells

Authors: Lu Zhang, Sang B. Kim, Ugur Eskiocak, Bruce Posner, Priyabrata Das, Woodring E. Wright, Jef K. De Brabander and Jerry W Shay

Citation: BMC Genomics 2014 15(Suppl 2):O3

Content type: Oral presentation

Published on: 2 April 2014
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Addition of metabolomics to the omics spectrum for cancer biomarker development– demonstration with the KrasG12D mouse model for pancreatic carcinoma

Authors: Evagelia C. Laiakis, Joseph J. LaConti, Amrita Cheema, Anton Wellstein and Albert J. Fornace Jr.

Citation: BMC Genomics 2014 15(Suppl 2):O4

Content type: Oral presentation

Published on: 2 April 2014
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Pharmacogenomics of CRC treatments: putting bricks on the path to personalized medicine

Authors: Ceres Fernández-Rozadilla, Emilia Balboa, Mahmood Rasool, Francisco Barros, Antoni Castells, Sergi Castellvi-Bel, Alejandro Brea-Fernández, Clara Ruiz-Ponte and Angel Carracedo

Citation: BMC Genomics 2014 15(Suppl 2):O5

Content type: Oral presentation

Published on: 2 April 2014
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Molecular characterization and identification of predictors of disease outcome in Saudi colorectal carcinoma

Authors: Abdelbaset Buhmeida, Ashraf Dallol, Jaudah Al-Maghrabi, Mahmoud Al-Ahwal, Abdulrahman Sibiany and Mohmmad Al-Qahtani

Citation: BMC Genomics 2014 15(Suppl 2):O6

Content type: Oral presentation

Published on: 2 April 2014
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Application of next generation sequencing in oncology

Authors: Brian Meyer

Citation: BMC Genomics 2014 15(Suppl 2):O7

Content type: Oral presentation

Published on: 2 April 2014
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How does Arab genome different from other genomes?

Authors: Ibrahim Abdulkareem

Citation: BMC Genomics 2014 15(Suppl 2):O8

Content type: Oral presentation

Published on: 2 April 2014
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Common threads: epigenetics, metabolism and the clock

Authors: Paolo Sassone-Corsi

Citation: BMC Genomics 2014 15(Suppl 2):O9

Content type: Oral presentation

Published on: 2 April 2014
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Nutritional genomics and metabolomics in obesity and type 2 diabetes

Authors: Frank B. Hu and Kothandaraman Narasimhan

Citation: BMC Genomics 2014 15(Suppl 2):O10

Content type: Oral presentation

Published on: 2 April 2014
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Epigenetic control of cell identity and plasticity

Authors: Valerio Orlando

Citation: BMC Genomics 2014 15(Suppl 2):O11

Content type: Oral presentation

Published on: 2 April 2014
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Understanding the phenotypic impact of non-coding sequence variation

Authors: Emmanouil Dermitzakis

Citation: BMC Genomics 2014 15(Suppl 2):O12

Content type: Oral presentation

Published on: 2 April 2014
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Next generation methods and tools for timing the evolution of species and strains

Authors: Sudhir Kumar and Koichiro Tamura

Citation: BMC Genomics 2014 15(Suppl 2):O13

Content type: Oral presentation

Published on: 2 April 2014
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Structural systems biology: from bacterial to cancer networks

Authors: Adam Godzik

Citation: BMC Genomics 2014 15(Suppl 2):O14

Content type: Oral presentation

Published on: 2 April 2014
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Solving genetic disease at the population scale

Authors: Barry Merriman

Citation: BMC Genomics 2014 15(Suppl 2):O15

Content type: Oral presentation

Published on: 2 April 2014
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Biomarkers of osteoarthritis: translating information from in vitro culture systems to human patients

Authors: Ali Mobasheri

Citation: BMC Genomics 2014 15(Suppl 2):O16

Content type: Oral presentation

Published on: 2 April 2014
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Unlocking the complexity of hypoxia non-coding transcriptome landscape of breast cancer

Authors: Hani Choudhry, Johannes Schodel, Ashwag Albukhari, Spyros Oikonomopoulos, Syed Haider, Daniela Moralli, Carme Camps, Francesca Buffa, Peter Ratcliffe, Ioannis Ragousis, David R. Mole and Adrian L. Harris

Citation: BMC Genomics 2014 15(Suppl 2):O17

Content type: Oral presentation

Published on: 2 April 2014
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Signaling in time and space

Authors: Norbert Perrimon

Citation: BMC Genomics 2014 15(Suppl 2):O18

Content type: Oral presentation

Published on: 2 April 2014
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Intracellular transport, molecular motors, KIFs and related diseases

Authors: Nobutaka Hirokawa

Citation: BMC Genomics 2014 15(Suppl 2):O19

Content type: Oral presentation

Published on: 2 April 2014
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Regulation of integrins and AKT signaling by miR-199-3p in HCMV-infected cells

Authors: Nouf N. Laqtom, Laura Kelly and Amy H. Buck

Citation: BMC Genomics 2014 15(Suppl 2):O20

Content type: Oral presentation

Published on: 2 April 2014
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The molecules and mechanisms of heart development, disease and regeneration

Authors: Eric N. Olson

Citation: BMC Genomics 2014 15(Suppl 2):O21

Content type: Oral presentation

Published on: 2 April 2014
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Autism and related neurodevelopmental disorders: the many genes involved

Authors: Stephen W. Scherer

Citation: BMC Genomics 2014 15(Suppl 2):O22

Content type: Oral presentation

Published on: 2 April 2014
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FGF negative regulation during early myogenesis

Authors: Muhammad Abu-Elmagd and Andrea Münsterberg

Citation: BMC Genomics 2014 15(Suppl 2):O23

Content type: Oral presentation

Published on: 2 April 2014
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Impact of sperm chromatin damage on natural fertility and ART success: evidence- based medicine

Authors: Ashok Agarwal

Citation: BMC Genomics 2014 15(Suppl 2):O24

Content type: Oral presentation

Published on: 2 April 2014
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Genetics of male infertility: status and prospects

Authors: Eberhard Nieschlag, Frank Tüttelmann and Mohammed A Beg

Citation: BMC Genomics 2014 15(Suppl 2):O25

Content type: Oral presentation

Published on: 2 April 2014
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The role of MTNR1B genetic polymorphisms in type 2 diabetes mellitus

Authors: Nehad Shaer, Jalaluddin J. Khan, Ashraf Dallol and Adel Abuzenadah

Citation: BMC Genomics 2014 15(Suppl 2):P1

Content type: Poster presentation

Published on: 2 April 2014
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Pharmacogenetics of CYP3A5 on Carbamazepine pharmacokinetics in epileptic patients developing toxicity

Authors: Mubarak Al-Gahtany, Gauthaman Karunakaran and Murali Munisamy

Citation: BMC Genomics 2014 15(Suppl 2):P2

Content type: Poster presentation

Published on: 2 April 2014
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Pharmacogenetics of uridine diphosphate glucuronosyltransferase (UGT2B7) genetic polymorphism on valproic acid pharmacokinetics in epilepsy

Authors: Murali Munisamy, Gauthaman Karunakaran, Mubarak Al-Gahtany, Vivekanandhan Subbiah and Manjari M Tripathi

Citation: BMC Genomics 2014 15(Suppl 2):P3

Content type: Poster presentation

Published on: 2 April 2014
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Trans-cellular transport of short chain fatty acids in the large intestine

Authors: Taoufik Nedjadi

Citation: BMC Genomics 2014 15(Suppl 2):P4

Content type: Poster presentation

Published on: 2 April 2014
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Hepatitis C virus core protein substitutions affect the response to pegylated-interferon and ribavirin therapy

Authors: Fatimah S. Alhamlan, Mohammed N. Al-Ahdal, Nisreen Z. Khalaf, Ayman A. Abdo, Faisal Sanai, Hamad I. Al-Ashgar and Ahmed A. Al-Qahtani

Citation: BMC Genomics 2014 15(Suppl 2):P5

Content type: Poster presentation

Published on: 2 April 2014
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Linkage analysis coupled with exome sequencing identified defects in gene ‘X’ causing premature ovarian insufficiency

Authors: Sulman Basit

Citation: BMC Genomics 2014 15(Suppl 2):P6

Content type: Poster presentation

Published on: 2 April 2014
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High throughput whole mitochondrial genome sequencing by two platforms of massively parallel sequencing

Authors: Seung Bum Seo, Xiangpei Zeng, Mourad Assidi, Bobby LaRue, Jonathan King, Antti Sajantila and Bruce Budowle

Citation: BMC Genomics 2014 15(Suppl 2):P7

Content type: Poster presentation

Published on: 2 April 2014
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A universal monoclonal antibody protects against all influenza A and B viruses by targeting a highly conserved epitope in the viral neuraminidase

Authors: Tracey M Doyle, Anwar M Hashem, Changgui Li, Doris J Bucher, Gary Van Domselaar, Junzhi Wang, Terry Cyr, Aaron Farnsworth, Runtao He, Aeron C Hurt, Earl G Brown and Xuguang Li

Citation: BMC Genomics 2014 15(Suppl 2):P8

Content type: Poster presentation

Published on: 2 April 2014
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Association of CYPA1 gene polymorphism with plasma nitric oxide levels in COPD

Authors: Ashrafunnisa Begum, Venkateshwari, Fazal Mohammed and A Jyothy

Citation: BMC Genomics 2014 15(Suppl 2):P9

Content type: Poster presentation

Published on: 2 April 2014
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Crystallography based structure elucidation of the complex of C-terminal fragment of Aβ polypeptide of Alzheimer’s disease with phospholipase A₂

Authors: Zeenat Mirza, Vikram Gopalakrishna Pillai, Sujata Sharma, Punit Kaur, Alagiri Srinivasan and Tej P. Singh

Citation: BMC Genomics 2014 15(Suppl 2):P10

Content type: Poster presentation

Published on: 2 April 2014
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CTLA-4 gene polymorphisms and risk of idiopathic recurrent pregnancy loss in a Tunisian population

Authors: Safia Messaoudi, Ilham Houas, Khadijah Yaseen, Mariem Dandana and Touhami Mahjoub

Citation: BMC Genomics 2014 15(Suppl 2):P11

Content type: Poster presentation

Published on: 2 April 2014
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Genetic variants in inflammatory cytokines and angiogenesis associated with diabetic nephropathy- A meta-analysis

Authors: Khalid Siddiqui, Dhekra Al-Naqeb, Sarah Al-Qassim and Nyla Nazir

Citation: BMC Genomics 2014 15(Suppl 2):P12

Content type: Poster presentation

Published on: 2 April 2014
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Cell adhesion molecules have prognostic potential in colorectal carcinoma

Authors: Asma’a AL-Attas, Abdulrhaman AlMalki, Mamdooh Gari, Shilu Mathew, Jaudah Al-Maghrabi, Mahmoud Al-Ahwal, Mohammed Al-Qahtani, Ashraf Dallol and Abdelbaset Buhmeida

Citation: BMC Genomics 2014 15(Suppl 2):P13

Content type: Poster presentation

Published on: 2 April 2014
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In silico characterization of a putative ORF-MAP1138c of Mycobacterium avium subspecies paratuberculosis(MAP) with its implications in virulence

Authors: Syed A Hassan, Seyed E Hasnain and Sami M Halawani

Citation: BMC Genomics 2014 15(Suppl 2):P14

Content type: Poster presentation

Published on: 2 April 2014
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“Stay in touch while on the bench” - how the MIQE applet can increase the quality of your qPCR and dPCR experiments

Authors: Afif M. Abdel Nour, Esam Azhar, Michael W. Pfaffl and Ghazi Damanhouri

Citation: BMC Genomics 2014 15(Suppl 2):P15

Content type: Poster presentation

Published on: 2 April 2014
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Role of cytokines in the interplay between cancer cells and stroma-associated monocytes

Authors: Taoufik Nedjadi and Eithne Costello

Citation: BMC Genomics 2014 15(Suppl 2):P16

Content type: Poster presentation

Published on: 2 April 2014
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Frizzled-7 expression during early cardiogenesis of Xenopus laevisembryo

Authors: Muhammad Abu-Elmagd and Grant Wheeler

Citation: BMC Genomics 2014 15(Suppl 2):P17

Content type: Poster presentation

Published on: 2 April 2014
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Fgf negative regulators control early chick somite myogenesis

Authors: Muhammad Abu-Elmagd, Katarzyna Goljanek-Whysall, Grant Wheeler and Andrea Münsterberg

Citation: BMC Genomics 2014 15(Suppl 2):P18

Content type: Poster presentation

Published on: 2 April 2014
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The clinical impact of CYP2C19 *2 and *3 polymorphism on Clopidogrel and cost analysis

Authors: Al Meman A, Khalaf H and Rasool Seemab

Citation: BMC Genomics 2014 15(Suppl 2):P19

Content type: Poster presentation

Published on: 2 April 2014
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Detection of rare single nucleotide variants affecting genes in the DNA repair pathways in hereditary breast cancer

Authors: Shireen Hussein, Adnan Merdad, Jaudah Al-Maghrabi, Mamdooh A. Gari, Fatma Al-Thubaiti, Ibtessam R. Hussein, Adeel G. Chaudhary, Adel M. Abuzenadah, Hanaa Tashkandi, Shadi Al-Khayyat, Taha Kumosani, Mohammed H. Al-Qahtani and Ashraf Dallol

Citation: BMC Genomics 2014 15(Suppl 2):P20

Content type: Poster presentation

Published on: 2 April 2014
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High-density microarray expression profiling in conventional papillary thyroid carcinomas with versus without a BRAF mutation

Authors: Reem Alotibi, Alaa Al-Ahmadi, Manar Ata, Sajjad Karim, Etimad Huwait, Mamdooh Gari, Mohammad Hussain Al-Qahtani, Hans-Juergen Schulten and Jaudah Al-Maghrabi

Citation: BMC Genomics 2014 15(Suppl 2):P21

Content type: Poster presentation

Published on: 2 April 2014
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Neu1 sialidase and matrix metalloproteinase-9 cross-talk in alliance with insulin receptors is an essential molecular signaling platform for insulin-induced receptor activation

Authors: Farah G. Alghamdi and Myron Szewczuk

Citation: BMC Genomics 2014 15(Suppl 2):P22

Content type: Poster presentation

Published on: 2 April 2014
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Endogenous controls in human umbilical vein endothelial cells under metabolic and oxidative stress

Authors: Sherin Bakhashab, Sahira Lari, Farid Ahmed, Hans-Juergen Schulten, Manikandan Jayapal, Sajjad Karim, Ayat Bashir, Fahad Ahmed, Abdulrahman Al-Malki, Hasan S Jamal, Mamdooh Gari, Mohammed H. Alqahtani, Ioakim Spyridopoulos and Jolanta U Weaver

Citation: BMC Genomics 2014 15(Suppl 2):P23

Content type: Poster presentation

Published on: 2 April 2014
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Deacetylation of Ku70 regulates ionizing-radiation induced DNA damage responses in human cells

Authors: Ahmed Al-Emam, Darren Arbon and Boris Kysela

Citation: BMC Genomics 2014 15(Suppl 2):P24

Content type: Poster presentation

Published on: 2 April 2014
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Azoospermia factor microdeletions: common tag STSs in infertile men with azoospermia and sever oligospermia from Egypt

Authors: Nasser A. Elhawary, Neveen S. Seif-Eldin, Marwa Zaki and Heba Diab

Citation: BMC Genomics 2014 15(Suppl 2):P25

Content type: Poster presentation

Published on: 2 April 2014
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